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Dr. Luis Lemus

E-mail: 
luis.lemus@usach.cl
Biografía: 

Doctor en Química, Universidad de Santiago de Chile, 2009. Chile

Licenciado en Química, Universidad de Santiago de Chile

Lineas de Investigación: 

Química inorgánica

Proyectos: 
  • Helicates as bioinspired cationic cylinders for selective DNA binding: Study of the mechanism of interaction and artificial nucleasa activity. Fondecyt Regular (No 1231787). 2023. 4 años. Investigador Responsable
  • Helicates as bioinspired cationic cylinders for selective DNA binding: study of the mechanism of interaction and artificial-nuclease activity. Fondecyt Regular (No 1190763). 2019. 4 años. Investigador Responsable
  • Spin and Chirality: New strategies for spin-dependent functionality in inorganic materials. Fondecyt Regular (No 1210325). 2021. 4 años Co-investigador
  • Study of Helicates as DNA Binders”. Fondecyt Iniciación en Investigación. (No 11130172) 2013. 4 años. Investigador Responsable
Últimas Publicaciones: 

14.- J. Cáceres-Vásquez, D.H. Jara, J. Costamagna, F. Martínez-Gómez, C. P. Silva, L. Lemus, E. Freire, R. Baggio, C. Vera,* J. Guerrero* (2023). Effect of non-covalent self-dimerization on the spectroscopic and electrochemical properties of mixed Cu(I) complexes. RSC ADVANCES

13.- M. Mallea, A. Acuña, H. Klahn, V. Artigas, F: Pavan,  F. Demarqui, L. Lemus, D. Jara,* P. Toro.* (2022). Cyrhetrenyl and Cymantrenyl N-Acylhydrazone Complexes Based on Isoniazid: Synthesis, Characterization, X-Ray Crystal Structures and Antitubercular Activity Evaluation. JOURNAL OF ORGANOMETALLIC  CHEMISTRY

12.- M. Ruiz, K. Perelmulter, P. Levín, A. Romo, L. Lemus, M. Fogolín, I. León,* A. Di Virgilio.* (2022). Antiproliferative Activity of Two Copper (II) Complexes on Colorectal Cancer Cell Models: Impact on ROS Production, Apoptosis Induction and NF-ΚB Inhibition. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

11.- L. Velasco, L. Llanos, P. Levín, A. Vega, J. Yu, X. Zhang, L. Lemus,* D. Aravena,* D. Moonshiram.* (2021). Structure and Excited-State Dynamics of Dimeric Copper(I) Photosensitizers Investigated by Time-Resolved X-Ray and Optical Transient Absorption Spectroscopy. PHYSICAL CHEMISTRY CHEMICAL PHYSICS

10.- A. Romo,* M. Carepo, P. Levín, O. Nascimento, D. Díaz, J. Rodríguez-López, I. León, L. Bezerra, L. Lemus, I. Diógenes.* (2021). Synergy of DNA Intercalation and Catalytic Activity of a Copper Complex towards Improved Polymerase Inhibition and Cancer Cell Cytotoxicity. DALTON TRANSACTIONS

9.- P. Levín, C. Ruiz, A. Romo, O. Nascimento, A. Di Virgilio, A. Oliver, P. Ayala, I. Diógenes,* I. León,* L. Lemus.* (2021). Water-Mediated Reduction of [Cu(Dmp)2(CH3CN)]2+: Implications of the Structure of a Classical Complex on Its Activity as an Anticancer Drug. INORGANIC CHEMISTRY FRONTIERS

8.- P. Levín, L. Balsa, C. Silva, A. Herzog, A. Vega, J. Pavez, I. León,* L. Lemus.* (2021). Artificial Chemical Nuclease and Cytotoxic Activity of a Mononuclear Copper(I) Complex and a Related Binuclear Double-Stranded Helicate. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

7.- C. Sun, L. Llanos, P. Arce, A. Oliver, R. Wannemacher,* J. Cabanillas-Gonzalez,* L. Lemus,* D. Aravena.* (2021). Nuclearity Control for Efficient Thermally Activated Delayed Fluorescence in a CuIComplex and Its Halogen-Bridged Dimer. CHEMISTRY OF MATERIALS

6.- L. Llanos, C. Vera, A. Vega, D. Aravena,* L. Lemus* (2020). Reactivity of CuIN4 Flattened Complexes: Interplay between Coordination Geometry and Ligand Flexibility INORGANIC CHEMISTRY

5.- P. Levín, D. Escudero, N. Díaz, A. Oliver, A. G. Lappin, G. Ferraudi,* L. Lemus* (2020). Structural and photochemical properties of Zn(II) phenanthroline-derived complexes: From mononuclear, to bimetallic and circular-trimetallic helicates INORGANIC CHEMISTRY

4.- R. Venegas, K. Muñoz-Becerra, L. Lemus, A. Toro-Labbé, J. H. Zagal,* F. J. Recio* (2019). Theoretical and Experimental Reactivity Predictors for the Electrocatalytic Activity of Copper Phenanthroline Derivatives for the Reduction of Dioxygen JOURNAL OF PHYSICAL CHEMISTRY.

3.- A. I. B. Romo, V. S. Dibo, D. S. Abreu, M. S. P. Carepo, A. C. Neira, I. Castillo, L. Lemus, O. R. Nascimento, P. V. Bernhardt, E. H. S. Sousa, I. C. N. Diógenes* (2019).
Ascorbyl and hydroxyl radical generation mediated by a copper complex adsorbed on gold DALTON TRANSACTIONS

2.- D. E. Díaz, L. Llanos, P.Arce, R. Lorca, J. Guerrero, J. Costamagna, D. Aravena, G. Ferraudi, A. Oliver, A. G. Lappin,* L. Lemus* (2018). Steric and electronic factors affecting the conformation of bimetallic Cu(I) complexes. Effect of the aliphatic spacer of tetracoordinating Schiff base ligands. CHEMISTRY-A EUROPEAN JOURNAL

1.- M.A.S. Silva, A. I.B. Romo, D. S. Abreu, M. S.P. Carepo, L. Lemus*, M.l Jafelicci, T. F. Paulo, O. R. Nascimento, E. Vargas, J. C. Denardin, I. C.N. Diógenes* (2018). Magnetic nanoparticles as a support for a copper (II) complex with nuclease activity. JOURNAL OF INORGANIC BIOCHEMISTRY.